Isozyme Associated with Premature Hemolysis
نویسنده
چکیده
From the Departments of Medicine and Pathology, University of California Los Angeles School of Medicine, Los Angeles, California 90024, and the Veterans Administration Center, Los Angeles, California 90073; the Departments of Pediatrics and Internal Medicine, University of Rochester School of Medicine and Strong Memorial Hospital, Rochester, New York 14620; and the Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03755
منابع مشابه
An inherited molecular lesion of erythrocyte pyruvate kinase. Identification of a kinetically aberrant isozyme associated with premature hemolysis.
Atypical cases of heritable hemolytic anemia have been noted that conform clinically and biochemically to anemias of the pyruvatekinase (PK)-deficient type, except for the presence of apparently adequate quantities of erythrocyte-PK activity by the usual assay procedure. Investigations of four such anomalous cases, occurring in two unrelated families, are presented. Erythrocytes contained a kin...
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تاریخ انتشار 2013